**NEW AND IMPROVED FORMULA**

NOW WITH A MARKET-LEADING 12MG OF ASTAXANTHIN PER 2 CAPSULES!!

Healthmasters HEMMLA

Hormone Stability
Energy
Mood/Brain
Metabolism
Lipid Profile
Antioxidant boost

This formula features Antarctic krill oil, which provides the omega-3 fatty acids (EPA and DHA) attached to phospholipids as well as to triglycerides.  Our krill oil is produced using a multi-stage oil (MSO®) extraction process that preserves the natural nutrient profile of krill oil while removing spoilage components, such as trimethylamine, total volatile nitrogen, and other oxidative elements and derivatives. The purity of K-Real combined with its phospholipid composition prevents the “fishy burps” associated with some fish oils. Clinical testing suggests that this molecular composition absorbs into red blood cells, reduces the n-6:n-3 PUFA ratio, and increases the omega-3 index more effectively than fish oil. Krill oil is also naturally complexed with astaxanthin, which provides powerful antioxidant activity and helps stabilize the oil.

Antarctic Krill

Krill, a cold water marine crustacean, is a rich source of omega-3 EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid). Healthmasters krill oil is extracted from krill biomass supplied only from vessels and facilities monitored by members of the Convention for the Conservation of Antarctic Marine Living Resources (CCAMLR). It is also five-star IKOS (International Krill Oil Standards) certified, which ensures the highest quality.

Omega-3 Fatty Acids

EPA and DHA, conditionally essential omega-3 fatty acids, have been extensively studied for their positive effects on cardiovascular health, cognitive integrity, immune function, and the body’s production of arachidonic acid-derived eicosanoids [1,2]. Research suggests that serum levels of EPA and DHA are inversely associated with cardiovascular health. In this regard, it is appropriate to note that the omega-3 index (a measurement of EPA and DHA in erythrocyte membranes) has become recognized as a biomarker of cardiovascular health [3,4].

Phospholipids

Considered the building blocks of healthy cells, phospholipids help maintain cell membrane fluidity and function. The phospholipid form of EPA and DHA is easily recognized, integrated, and utilized by the body’s cells. The major phospholipid in HEMMLA is phosphatidylcholine, which is highly concentrated in the heart, brain, liver, and kidneys [5].

Astaxanthin

Both animal and clinical research suggest that astaxanthin, a red-orange member of the carotenoid family, supports antioxidant mechanisms and helps promote a healthy cytokine balance in the body [6]. Krill is recognized as a rich source of astaxanthin, which not only provides health benefits but also serves to stabilize the krill oil [7,8].

Research

In a double-blind, placebo-controlled, crossover design, the effects of krill oil (3g/d) on plasma and red blood cell fatty acid profile was studied in healthy volunteers. Results indicated that K•Real krill oil more effectively increased plasma and red blood cell EPA and DHA concentrations, decreased the total n-6:n-3 PUFA ratio, and increased the omega-3 index compared to fish oil. These findings suggest that the bioavailability of krill oil omega-3 PUFA might be more pronounced than that of fish oil, which is likely due to the structural differences between these two marine oils. Krill oil was well tolerated with no adverse events [9].

In another randomized, double-blind controlled crossover trial involving 47 participants, krill oil supplementation was shown to support cardiovascular health by improving endothelial function and supporting healthy blood lipid metabolism. Participants presented improved endothelial function after taking krill oil daily for four weeks compared to participants taking olive oil. During the additional 17-week supplementation period, 34 of the participants showed a statistically significant improvement in endothelial function and lipid metabolism when compared with their respective baseline measures [10].

HEMMLA- is formulated to provide clinical dietary management of omega-3 phospholipid deficiency which may be associated with mild-to-moderate hypertriglyceridemia; and to support cell membrane fluidity, normal homocysteine metabolism, and cardiometabolic health. - 

No Benzene
No Acetone
No Solvents

References

1. Linus Pauling Institute.
2. DHA, EPA, Omega-3 Institute: The Source for Objective Science-based DHA/ EPA Omega-3 Information. http://www.dhaomega3.org. Accessed October 5, 2016.
3. Pottala JV, Garg S, Cohen BE, et al. Blood eicosapentaenoic and docosahexaenoic acids predict all-cause mortality in patients with stable coronary heart disease: the Heart and Soul study. Circ Cardiovasc Qual Outcomes. 2010 Jul;3(4):406-12. [PMID: 20551373]
4. Harris WS. The omega-3 index as a risk factor for coronary heart disease. Am J Clin Nutr. 2008 Jun;87(6):1997S-2002S. [PMID: 18541601]
5. Phosphatidylcholine. Natural Standard Database. http://naturalstandard.com/ databases/herbssupplements/phosphatidylcholine.asp. Accessed October 5, 2016.
6. Hussein G, Sankawa U, Goto et al. Astaxanthin, a carotenoid with potential in human health and nutrition. J Nat Prod. 2006 Mar;69(3):443-9. Review. [PMID: 16562856]
7. Tou JC, Jaczynski J, Chen YC. Krill for human consumption: nutritional value and potential health benefits. Nutr Rev. 2007 Feb;65(2):63-77. [PMID: 17345959]
8. Kidd PM. Omega-3 DHA and EPA for cognition, behavior, and mood: clinical findings and structural-functional synergies with cell membrane phospholipids. Altern Med Rev. 2007 Sep;12(3):207-27. [PMID: 18072818]
9. Ramprasath VR, Eyal I, Zchut S, et al. Enhanced increase of omega-3 index in healthy individuals with response to 4-week n-3 fatty acid supplementation from krill oil versus fish oil. Lipids Health Dis. 2013 Dec 5;12:178. [PMID: 24304605]
10. Lobraico JM, DiLello LC, Butler AD, et al. Effects of krill oil on endothelial function and other cardiovascular risk factors in participants with type 2 diabetes, a randomized controlled trial. BMJ Open Diabetes Res Care. 2015 Oct 14;3(1):e000107. [PMID: 26504524]

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